Lucigenin

Lucigenin is a chemiluminescence probe. Lucigenin can be used to detect the production of endogenous superoxide anion radical (O2-) . Lucigenin is extremely sensitive to chloride ions, while it combined with chloride ions, the fluorescence will be quenched. Lucigenin also can be used as a chloride indicator. Ex/Em=455/505 nm[1].

Product Specifications

CAS Number

[2315-97-1]

Product Name Alternative

NSC-151912; L-6868

UNSPSC

12171500

Hazard Statement

H272, H315, H319

Target

Fluorescent Dye; Reactive Oxygen Species (ROS)

Type

Dye Reagents

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/Lucigenin.html

Purity

99.12

Solubility

DMSO : 58.33 mg/mL (ultrasonic)

Smiles

C[N+]1=C2C=CC=CC2=C(C3=C4C=CC=CC4=[N+](C)C5=C3C=CC=C5)C6=C1C=CC=C6.O=N([O-])=O.O=N([O-])=O

Molecular Formula

C28H22N4O6

Molecular Weight

510.50

Precautions

H272, H315, H319

References & Citations

[1]Li Y, et al. Validation of lucigenin (bis-N-methylacridinium) as a chemilumigenic probe for detecting superoxide anion radical production by enzymatic and cellular systems. J Biol Chem. 1998 Jan 23;273 (4) :2015-23.