Antibacterial agent 195
Product Specifications
UNSPSC Description
Antibacterial agent 195 (compound A20), a Matrine (HY-N0164) derivative, is a potent antibiotic. Antibacterial agent 195 shows antibacterial activity against Gram-positive bacterium (MICS.aureus=0.021 mg/mL; MICP.acnes=0.030 mg/mL), Gram-negative bacterium (MICE.coli=0.092 mg/mL; MICC.albicans=0.379 mg/mL) and Fungus (MIC=2.806 mg/mL)[1].
Target Antigen
Antibiotic; Bacterial; Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/antibacterial-agent-195.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC2=C(C=C(CC3=CC=C(C(F)(F)F)C=C3)C=C2)N1)N4[C@@](CCCC(OC)=O)([H])[C@]5([H])[C@](N6CCC5)([H])[C@](CCC6)([H])C4
Molecular Weight
581.67
References & Citations
[1]Yufang Li, et al. Synthesis, antibacterial activity, and 3D-QASR studies of matrine-indole derivatives as potential antibiotics. Bioorg Med Chem Lett. 2024 Feb 21:102:129671.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162329/Antibacterial-agent-195-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162329/
Clinical Information
No Development Reported
CAS Number
9007-83-4
Curated Selection
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