Benzydamine

Benzydamine is an orally administered prostaglandin synthesis inhibitor that has anti-inflammatory, analgesic, antipyretic, and antibacterial properties. Benzydamine can inhibit TNF-α, stabilize cell membranes, and reduce oxidative stress within cells[1][2][3].

Product Specifications

CAS Number

[642-72-8]

UNSPSC

12352005

Hazard Statement

H302

Target

Bacterial; PGE synthase; TNF Receptor

Type

Reference compound

Related Pathways

Anti-infection; Apoptosis; Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/benzydamine.html

Solubility

10 mM in DMSO

Smiles

CN(C)CCCOC1=NN(CC2=CC=CC=C2)C3=C1C=CC=C3

Molecular Formula

C19H23N3O

Molecular Weight

309.41

Precautions

P264-P270-P330-P501

References & Citations

[1]Quane PA, Pharmacology of benzydamine. Inflammopharmacology. 1998;6 (2) :95-107|[2]Fanaki NH, et al. Antimicrobial activity of benzydamine, a non-steroid anti-inflammatory agent. J Chemother. 1992 Dec;4 (6) :347-52.|[3]R S Turnbull, et al. Benzydamine Hydrochloride (Tantum) in the management of oral inflammatory conditions. J Can Dent Assoc. 1995 Feb;61 (2) :127-34.