LDHA-IN-6
LDHA-IN-6 (compound 6) is an oral bioactive inhibitor of lactate dehydrogenase-A (LDHA), with the IC50 of 46 nM. LDHA-IN-6 has antitumor activity[1].
Product Specifications
CAS Number
3043790-18-4
UNSPSC
12352005
Target
Lactate Dehydrogenase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ldha-in-6.html
Smiles
O=C(OC)C(C1=CC=C(C(F)(F)F)C=C1)CC(NC2=CC=C(C(C3=NC=CN3C)=O)C=C2)=O
Molecular Formula
C23H20F3N3O4
Molecular Weight
459.42
References & Citations
[1]Horrick Sharma, et al. Synthesis and biological characterization of an orally bioavailable lactate dehydrogenase-A inhibitor against pancreatic cancer. Eur J Med Chem. 2024 Jun 17:275:116598.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
LDHA
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