Anti-Hu C3aR Alexa Fluor® 647
C3aR is a 7TM transmembrane protein associated with G proteins, and serves as a receptor for C3a complement fragment. It is expressed mainly on neutrophils, mast cells, basophils, eosinophils, dendritic cells, monocytes, and macrophages. Upon detection of its ligand, the activated C3aR signaling cascade results in degranulation, superoxide production, and chemotaxis.
Product Specifications
Certification
RUO
Reactivity
Human
Immunogen
Human C3aR transfectants
Target Antigen
C3aR
Clone
HC3aRZ8
Applications
FC (QC tested), IHC-F
Format
Alexa Fluor® 647
Buffer
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations
Storage Conditions
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Specificity
The mouse monoclonal antibody HC3aRZ8 recognizes an extracellular epitope of C3aR, a transmembrane chemotactic receptor for C3a anaphylatoxin.
Applications Notes
6
Isotype
Mouse IgG2b
Frequently Asked Questions
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