Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Ampreloxetine (hydrochloride)

Ampreloxetine (TD-9855) hydrochloride is an orally active and CNS-penetrant inhibitor of Norepinephrine transporter (NET) and Serotonin 5-HT uptake transporter (SERT), but not Dopamine transporter (DAT) . Ampreloxetine hydrochloride binds norepinephrine transporters (NET) and serotonin transporters (SERT) with EC50 values of 11.7 ng/mL and 50.8 ng/mL, respectively, in plasma[1].

Product Specifications

CAS Number

1227056-87-2

Product Name Alternative

TD-9855 (hydrochloride)

UNSPSC

12352005

Target

Serotonin Transporter

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ampreloxetine-hydrochloride.html

Purity

99.47

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

FC1=C(C(F)=CC(F)=C1)OCC2=C(C3CCNCC3)C=CC=C2.Cl

Molecular Formula

C18H19ClF3NO

Molecular Weight

357.80

References & Citations

[1]Smith JA, et al. Preclinical to clinical translation of CNS transporter occupancy of TD-9855, a novel norepinephrine and serotonin reuptake inhibitor. Int J Neuropsychopharmacol. 2014 Dec 13;18 (2) :pyu027.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

Phase 3

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

P53 Tumor Suppressor Protein (rTP53/1739), CF740 conjugate, 0.1mg/mL
BNC742091-100 1x 100 µL

P53 Tumor Suppressor Protein (rTP53/1739), CF740 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
MMP-12 Recombinant Rabbit monoclonal Antibody
HA750052 100 µL

MMP-12 Recombinant Rabbit monoclonal Antibody

Sign In for Pricing
View Details
BMP10 Rabbit Polyclonal Antibody
HA500312 100 µL

BMP10 Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
Hspa5 Rat Monoclonal Antibody [Clone ID: 76-E6]
AM08058BT-N 500 µg

Hspa5 Rat Monoclonal Antibody [Clone ID: 76-E6]

Sign In for Pricing
View Details
MMP9 (MMP9/2025R), CF740 conjugate, 0.1mg/mL
BNC742025-500 1x 500 µL

MMP9 (MMP9/2025R), CF740 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
ENPP2 Rabbit Polyclonal Antibody
AP05178PU-N 100 µg

ENPP2 Rabbit Polyclonal Antibody

Sign In for Pricing
View Details