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STING agonist-7

Product Specifications

UNSPSC Description

STING agonist-7 is a non-nucleotide STING agonist. STING agonist-7 binds selectively to mouse STING but not human STING. STING agonist-7 penetrates cell membrane poorly[1].

Target Antigen

STING

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/sting-agonist-7.html

Solubility

DMSO : 62.5 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=CC2=C1OC(CNC(C3=C4N=CC=CN4N=C3)=O)=C2)O

Molecular Weight

336.30

References & Citations

[1]Emily C Cherney, et al. Discovery of Non-Nucleotide Small-Molecule STING Agonists via Chemotype Hybridization. J Med Chem. 2022 Feb 24;65(4):3518-3538.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-143896/STING-agonist-7-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-143896/STING-agonist-7-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

2767442-46-4

Available Sizes

Curated Selection

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