ELAAWCRWGFLLALLPPGIAG (TFA)

ELAAWCRWGFLLALLPPGIAG TFA (P5) is derived from rat HER2/neu protein with 21 amino acid length (aa 5-25) . ELAAWCRWGFLLALLPPGIAG TFA can induce cytotoxic T lymphocyte (CTL) responses in mice bearing HER2-positive tumours[1].

Product Specifications

UNSPSC

12352209

Target

EGFR

Type

Peptides

Related Pathways

JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/elaawcrwgfllallppgiag-tfa.html

Solubility

10 mM in DMSO

Smiles

O=C(N1[C@@H](CCC1)C(N2[C@@H](CCC2)C(NCC(N[C@@H]([C@@H](C)CC)C(N[C@@H](C)C(NCC(O)=O)=O)=O)=O)=O)=O)[C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CC3=CC=CC=C3)NC(CNC([C@H](CC4=CNC5=CC=CC=C45)NC([C@H](CCCNC(N)=N)NC([C@H](CS)NC([C@@H](NC([C@H](C)NC([C@H](C)NC([C@H](CC(C)C)NC([C@@H](N)CCC(O)=O)=O)=O)=O)=O)CC6=CNC7=CC=CC=C67)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.O=C(C(F)(F)F)O.[x]

Molecular Formula

C109H164N26O24S.xC2HF3O2

Molecular Weight

2254.69 (free acid)

References & Citations

[1]Zahra Gholizadeh, et al. Enhanced immune response induced by P5 HER2/neu-derived peptide-pulsed dendritic cells as a preventive cancer vaccine. J Cell Mol Med. 2018 Jan;22 (1) :558-567.