InhA-IN-8
InhA-IN-8 (compound 6c) is an orally active inhibitor of Mycobacterium tuberculosis InhA (enoyl ACP reductase) . InhA-IN-8 has good inhibitory activity against Mtb UalRv (MIC = 0.5-1 μg/mL) . InhA-IN-8 can be used in research on acute tuberculosis model mice[1].
Product Specifications
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/inha-in-8.html
Smiles
CC1=CC=CC(C2=C(C3=C(C(Br)=CS3)NC2=O)O)=C1
Molecular Formula
C14H10BrNO2S
Molecular Weight
336.20
References & Citations
[1]Liang L, Liu Z, et al. Design and synthesis of Thieno[3, 2-b]pyridinone derivatives exhibiting potent activities against Mycobacterium tuberculosis in vivo by targeting Enoyl-ACP reductase. Eur J Med Chem. 2024 Aug 31;279:116806.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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