InhA-IN-8

InhA-IN-8 (compound 6c) is an orally active inhibitor of Mycobacterium tuberculosis InhA (enoyl ACP reductase) . InhA-IN-8 has good inhibitory activity against Mtb UalRv (MIC = 0.5-1 μg/mL) . InhA-IN-8 can be used in research on acute tuberculosis model mice[1].

Product Specifications

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/inha-in-8.html

Smiles

CC1=CC=CC(C2=C(C3=C(C(Br)=CS3)NC2=O)O)=C1

Molecular Formula

C14H10BrNO2S

Molecular Weight

336.20

References & Citations

[1]Liang L, Liu Z, et al. Design and synthesis of Thieno[3, 2-b]pyridinone derivatives exhibiting potent activities against Mycobacterium tuberculosis in vivo by targeting Enoyl-ACP reductase. Eur J Med Chem. 2024 Aug 31;279:116806.