Human ACTN1 protein

<strong>Human ACTN1 protein</strong>_x000D_ <strong>Catalog number:</strong> B2010964_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 31.4 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> BDPLT15 protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Westbury SK, Shoemark DK, Mumford AD. ACTN1 variants associated with thrombocytopenia Platelets. 2017 Sep;28(6):625-627._x000D_ 2: Vincenot A, Saultier P, Kunishima S, Poggi M, Hurtaud-Roux MF, Roussel A, Actn Study Coinvestigators, Schlegel N, Alessi MC. Novel ACTN1 variants in cases of thrombocytopenia Hum Mutat. 2019 Dec;40(12):2258-2269._x000D_ 3: Chen Q, Zhou XW, Zhang AJ, He K. ACTN1 supports tumor growth by inhibiting Hippo signaling in hepatocellular carcinoma J Exp Clin Cancer Res. 2021 Jan 7;40(1):23._x000D_ 4: Sharma P, Shathasivam T, Ignatchenko V, Kislinger T, Gramolini AO. Identification of an FHL1 protein complex containing ACTN1, ACTN4, and PDLIM1 using affinity purifications and MS-based protein-protein interaction analysis Mol Biosyst. 2011 Apr;7(4):1185-96._x000D_ 5: Xie GF, Zhao LD, Chen Q, Tang DX, Chen QY, Lu HF, Cai JR, Chen Z. High ACTN1 Is Associated with Poor Prognosis, and ACTN1 Silencing Suppresses Cell Proliferation and Metastasis in Oral Squamous Cell Carcinoma Drug Des Devel Ther. 2020 May 5;14:1717-1727._x000D_ 6: Faleschini M, Melazzini F, Marconi C, Giangregorio T, Pippucci T, Cigalini E, Pecci A, Bottega R, Ramenghi U, Siitonen T, Seri M, Pastore A, Savoia A, Noris P. ACTN1 mutations lead to a benign form of platelet macrocytosis not always associated with thrombocytopenia Br J Haematol. 2018 Oct;183(2):276-288._x000D_ 7: Zhang S, Wang J, Chen T, Wang J, Wang Y, Yu Z, Zhao K, Zheng K, Chen Y, Wang Z, Li B, Wang C, Huang W, Fu Z, Chen J. α-Actinin1 promotes tumorigenesis and epithelial-mesenchymal transition of gastric cancer via the AKT/GSK3β/β-Catenin pathway Bioengineered. 2021 Dec;12(1):5688-5704._x000D_ 8: Bottega R, Marconi C, Faleschini M, Baj G, Cagioni C, Pecci A, Pippucci T, Ramenghi U, Pardini S, Ngu L, Baronci C, Kunishima S, Balduini CL, Seri M, Savoia A, Noris P. ACTN1-related thrombocytopenia: identification of novel families for phenotypic characterization Blood. 2015 Jan 29;125(5):869-72._x000D_ 9: Lee Y, Pujol Canadell M, Shuryak I, Perrier JR, Taveras M, Patel P, Koller A, Smilenov LB, Brenner DJ, Chen EI, Turner HC. Candidate protein markers for radiation biodosimetry in the hematopoietically humanized mouse model Sci Rep. 2018 Sep 10;8(1):13557._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/34802252">10: Lindholm ME, Jimenez-Morales D, Zhu H, Seo K, Amar D, Zhao C, Raja A, Madhvani R, Abramowitz S, Espenel C, Sutton S, Caleshu C, Berry GJ, Motonaga KS, Dunn K, Platt J, Ashley EA, Wheeler MT. Mono- and Biallelic Protein-Truncating Variants in Alpha-Actinin 2 Cause Cardiomyopathy Through Distinct Mechanisms Circ Genom Precis Med. 2021 Dec;14(6):e003419. </a>_x000D_ _x000D_ <strong>Products Related to Human ACTN1 protein</strong><a href="https://moleculardepot.com/product-category/Proteins/">: Proteins</a>