NSC-124854
NSC-124854 is a DNA polymerase β (Pol-β) inhibitor with an IC50 of 5.3 μM. NSC-124854 has antitumor activity[1].
Product Specifications
CAS Number
1033942-30-1
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nsc-124854.html
Smiles
OP(OCC1OC(N2C(I)CC(N)=NC2=O)CC1O)(O)=O
Molecular Formula
C9H15IN3O7P
Molecular Weight
435.11
References & Citations
[1]Jaiswal AS, et al. DNA polymerase β as a novel target for chemotherapeutic intervention of colorectal cancer. PLoS One. 2011 Feb 2;6 (2) :e16691.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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