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NSC-124854

NSC-124854 is a DNA polymerase β (Pol-β) inhibitor with an IC50 of 5.3 μM. NSC-124854 has antitumor activity[1].

Product Specifications

CAS Number

1033942-30-1

UNSPSC

12352005

Target

DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nsc-124854.html

Smiles

OP(OCC1OC(N2C(I)CC(N)=NC2=O)CC1O)(O)=O

Molecular Formula

C9H15IN3O7P

Molecular Weight

435.11

References & Citations

[1]Jaiswal AS, et al. DNA polymerase β as a novel target for chemotherapeutic intervention of colorectal cancer. PLoS One. 2011 Feb 2;6 (2) :e16691.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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