JMV-1645
JMV-1645 is a potent and selective B1 bradykinin receptor antagonist with a Ki value of 0.023 nM on the human cloned B1 receptor. JMV-1645 can be utilized in trauma and infection research[1].
Product Specifications
CAS Number
284037-77-0
UNSPSC
12352209
Target
Bradykinin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/jmv-1645.html
Smiles
O=C(N(C1=CC=CC=C1SC2)CC(O)=O)[C@@H]2NC([C@H](CO)NC([C@H](C3CC4=CC=CC=C4C3)NC(CNC([C@H]5N(C[C@@H](C5)O)C([C@H]6N(CCC6)C([C@H](CCCNC(N)=N)NC([C@@H](N)CCCCN)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C49H69N13O12S
Molecular Weight
1064.22
References & Citations
[1]Bedos P, et al. A rational approach to the design and synthesis of a new bradykinin B (1) receptor antagonist. J Med Chem. 2000 Jun 15;43 (12) :2387-94.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
Bradykinin B1 Receptor (B1R)
Frequently Asked Questions
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