PM-43I
PM-43I is a potent STAT6 inhibitor and can reduce STAT6 phosphorylation level. PM-43I can be used in allergic lung disease, allergic rhinitis, chronic pulmonary obstructive disease and cancer research[1].
Product Specifications
CAS Number
1637532-77-4
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
STAT
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pm-43i.html
Purity
99.75
Solubility
DMSO : 35 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CC(C)(C)C(OCOP(C(F)(C1=CC=C(C=C1)/C(C)=C/C(N[C@@H]2C(N(CCCC2)CC(N(C3=CC=CC=C3)C)=O)=O)=O)F)(OCOC(C(C)(C)C)=O)=O)=O
Molecular Formula
C38H50F2N3O10P
Molecular Weight
777.79
Precautions
H302, H315, H319, H335
References & Citations
[1]John S. Mcmurray, et al. Stat6 inhibitors. WO2014182928A2.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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