Tezacitabine
Tezacitabine is a cytostatic and cytotoxic antimetabolite and a nucleoside analogue. Tezacitabine irreversibly inhibits the ribonucleotide reductase and interferes with DNA replication and repair. Tezacitabine effectively induces cells apoptotic. Tezacitabine has the potential for leukemias and solid tumors (carcinomas) treatment[1][2].
Product Specifications
CAS Number
130306-02-4
UNSPSC
12352005
Target
Apoptosis; DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tezacitabine.html
Concentration
10mM
Purity
99.97
Solubility
DMSO : 200 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
F/C=C1[C@H](N2C(N=C(N)C=C2)=O)O[C@H](CO)[C@H]/1O
Molecular Formula
C10H12FN3O4
Molecular Weight
257.22
References & Citations
Shipping Conditions
Dry Ice
Storage Conditions
-80°C
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Frequently Asked Questions
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