L 858051
L 858051 is an analog of Forskolin that activates adenylate cyclase while also having modulatory effects on intracellular cAMP levels, particularly enhancing the CNG current in cardiac myocytes[1].
Product Specifications
CAS Number
110452-75-0
Product Name Alternative
7DMB-Forskolin (free base)
UNSPSC
12352005
Target
Adenylate Cyclase
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/l-858051.html
Smiles
O=C(CCCN1CCN(CC1)C)O[C@H]2[C@H]([C@]3(C(C)(CC[C@@H]([C@@]3([C@@]4([C@@]2(O[C@@](C=C)(CC4=O)C)C)O)C)O)C)[H])O
Molecular Formula
C29H48N2O7
Molecular Weight
536.70
References & Citations
[1]Negative feedback exerted by cAMP-dependent protein kinase and cAMP phosphodiesterase on subsarcolemmal cAMP signals in intact cardiac myocytes: an in vivo study using adenovirus-mediated expression of CNG channels
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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