Human PCAF Histone Acetyltransferase

<strong>Human PCAF Histone Acetyltransferase</strong>_x000D_ <strong>Catalog number:</strong> B2017235_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> ~40 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80°C_x000D_ <strong>Keywords:</strong> HAT, p300/(CREB binding protein) Associated Factor_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Tchakarska G, Sola B. The double dealing of cyclin D1 Cell Cycle. 2020 Jan;19(2):163-178._x000D_ 2: Malatesta M, Steinhauer C, Mohammad F, Pandey DP, Squatrito M, Helin K. Histone acetyltransferase PCAF is required for Hedgehog-Gli-dependent transcription and cancer cell proliferation Cancer Res. 2013 Oct 15;73(20):6323-33._x000D_ 3: Brockmann D, Lehmkühler O, Schmücker U, Esche H. The histone acetyltransferase activity of PCAF cooperates with the brahma/SWI2-related protein BRG-1 in the activation of the enhancer A of the MHC class I promoter Gene. 2001 Oct 17;277(1-2):111-20._x000D_ 4: Jiang H, Lu H, Schiltz RL, Pise-Masison CA, Ogryzko VV, Nakatani Y, Brady JN. PCAF interacts with tax and stimulates tax transactivation in a histone acetyltransferase-independent manner Mol Cell Biol. 1999 Dec;19(12):8136-45._x000D_ 5: Kornacki JR, Stuparu AD, Mrksich M. Acetyltransferase p300/CBP associated Factor (PCAF) regulates crosstalk-dependent acetylation of histone H3 by distal site recognition ACS Chem Biol. 2015 Jan 16;10(1):157-64._x000D_ 6: Schiltz RL, Mizzen CA, Vassilev A, Cook RG, Allis CD, Nakatani Y. Overlapping but distinct patterns of histone acetylation by the human coactivators p300 and PCAF within nucleosomal substrates J Biol Chem. 1999 Jan 15;274(3):1189-92._x000D_ 7: Okumura K, Mendoza M, Bachoo RM, DePinho RA, Cavenee WK, Furnari FB. PCAF modulates PTEN activity J Biol Chem. 2006 Sep 8;281(36):26562-8._x000D_ 8: Lau OD, Courtney AD, Vassilev A, Marzilli LA, Cotter RJ, Nakatani Y, Cole PA. p300/CBP-associated factor histone acetyltransferase processing of a peptide substrate. Kinetic analysis of the catalytic mechanism J Biol Chem. 2000 Jul 21;275(29):21953-9._x000D_ 9: Modak R, Basha J, Bharathy N, Maity K, Mizar P, Bhat AV, Vasudevan M, Rao VK, Kok WK, Natesh N, Taneja R, Kundu TK. Probing p300/CBP associated factor (PCAF)-dependent pathways with a small molecule inhibitor ACS Chem Biol. 2013;8(6):1311-23._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/24944246">10: Xiong Y, Svingen PA, Sarmento OO, Smyrk TC, Dave M, Khanna S, Lomberk GA, Urrutia RA, Faubion WA Jr. Differential coupling of KLF10 to Sin3-HDAC and PCAF regulates the inducibility of the FOXP3 gene Am J Physiol Regul Integr Comp Physiol. 2014 Sep 15;307(6):R608-20. </a>_x000D_ _x000D_ <strong>Products Related to Human PCAF Histone Acetyltransferase can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>