Polyhexamethyleneguanidine (hydrochloride)

Polyhexamethyleneguanidine (PHMGH) hydrochloride is a positively charged polymer with broad-spectrum antimicrobial activity. It exerts its antibacterial effects by binding to the cell membranes of bacteria and fungi, disrupting membrane integrity. Polyhexamethyleneguanidine hydrochloride can be applied in studies related to disinfection, water treatment, pesticides, and other fields[1][2]</su

Product Specifications

CAS Number

[57028-96-3]

Product Name Alternative

PHMGH

UNSPSC

12352211

Hazard Statement

H302, H315, H317, H318, H335, H410

Target

Antibiotic; Bacterial; Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/polyhexamethyleneguanidine-hydrochloride.html

Purity

70.0

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

N=C(NCCCCCCC)NC.[H]Cl.[F,Cl,Br,I].[n]

Molecular Formula

(C6H16N2.CH5N3.HCl) x

Precautions

H302, H315, H317, H318, H335, H410

References & Citations

[1]Wei D, et al. Structural characterization and antibacterial activity of oligoguanidine (polyhexamethylene guanidine hydrochloride) [J]. Materials Science and Engineering: C, 2009, 29 (6) : 1776-1780.|[2]Choi H, et al. Antifungal activity of the cationic antimicrobial polymer-polyhexamethylene guanidine hydrochloride and its mode of action[J]. Fungal biology, 2017, 121 (1) : 53-60.