Anti-Mouse LAG-3 Antibody (C9B7W)

Anti-Mouse LAG-3 Antibody (C9B7W) is an anti-mouse LAG-3 IgG1 monoclonal antibody. Anti-Mouse LAG-3 Antibody (C9B7W) can enhance CD4+ T cell function and exert anti-tumor effects without blocking the interaction between LAG-3 and MHCII. Anti-Mouse LAG-3 Antibody (C9B7W) can be used for research on cancer such as head and neck squamous cell carcinoma (HNSCC) [1][2][3].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352203

Hazard Statement

H302, H315, H319, H335

Target

LAG-3

Type

Inhibitory Antibodies

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-mouse-lag-3-antibody-c9b7w.html

Purity

Solubility

H2O

Smiles

[Anti-MouseLAG-3Antibody(C9B7W)]

Molecular Weight

(150 kDa)

Precautions

H302, H315, H319, H335

References & Citations

[1]Cemerski, S., et al. T cell activation and anti-tumor efficacy of anti-LAG-3 antibodies is independent of LAG-3 – MHCII blocking capacity. j. immunotherapy cancer 3 (Suppl 2), P183 (2015) . |[2]Wang X, et al. Resistance to anti-LAG-3 plus anti-PD-1 therapy in head and neck cancer is mediated by Sox9+ tumor cells interaction with Fpr1+ neutrophils. Nat Commun. 2025 Apr 28;16 (1) :3975.|[3]Thudium K, et al. Preclinical Characterization of Relatlimab, a Human LAG-3-Blocking Antibody, Alone or in Combination with Nivolumab. Cancer Immunol Res. 2022 Oct 4;10 (10) :1175-1189.