Ebelactone A

<strong>Ebelactone A</strong> <strong>Catalog number:</strong> MDP0534 <strong>CAS Number: </strong>136132-68-8 <strong>Sequence: </strong>3,11-Dihydroxy-2,4,6,8,10,12-hexamethyl-9-oxo-(E)-6-tetradecen-3-olide <strong>Amount:</strong> 5 mg <strong>Molecular Weight:</strong> 338.4 g/mol <strong>Supplied as:</strong> Powder <strong>Applications:</strong> molecular tool for various biochemical applications <strong>Storage:</strong> -20 °C <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals. <strong>Grade:</strong> Biotechnology grade. All products are highly pure. <strong>References:</strong> 1: Wyatt MA, Ahilan Y, Argyropoulos P, Boddy CN, Magarvey NA, Harrison PH. Biosynthesis of ebelactone A: isotopic tracer, advanced precursor and genetic studies reveal a thioesterase-independent cyclization to give a polyketide β-lactone J Antibiot (Tokyo). 2013 Jul;66(7):421-30. 2: Nonaka Y, Ohtaki H, Ohtsuka E, Kocha T, Fukuda T, Takeuchi T, Aoyagi T. Effects of ebelactone B, a lipase inhibitor, on intestinal fat absorption in the rat J Enzyme Inhib. 1996;10(1):57-63. 3: Uotani K, Naganawa H, Aoyagi T, Umezawa H. Biosynthetic studies of ebelactone A and B by 13C NMR spectrometry J Antibiot (Tokyo). 1982 Dec;35(12):1670-4. 4: Archibald SC, Barden DJ, Bazin JF, Fleming I, Foster CF, Mandal AK, Mandal AK, Parker D, Takaki K, Ware AC, Williams AR, Zwicky AB. Stereocontrol in organic synthesis using silicon-containing compounds. Studies directed towards the synthesis of ebelactone A Org Biomol Chem. 2004 Apr 7;2(7):1051-64. 5: Uotani K, Naganawa H, Kondo S, Aoyagi T, Umezawa H. Structural studies on ebelactone A and B, esterase inhibitors produced by actinomycetes J Antibiot (Tokyo). 1982 Nov;35(11):1495-9. 6: Mandal AK. Stereocontrolled total synthesis of (-)-ebelactone A Org Lett. 2002 Jun 13;4(12):2043-5. 7: De Pascale G, Nazi I, Harrison PH, Wright GD. β-Lactone natural products and derivatives inactivate homoserine transacetylase, a target for antimicrobial agents J Antibiot (Tokyo). 2011 Jul;64(7):483-7. 8: Burnette TC, Harrington JA, Reardon JE, Merrill BM, de Miranda P. Purification and characterization of a rat liver enzyme that hydrolyzes valaciclovir, the L-valyl ester prodrug of acyclovir J Biol Chem. 1995 Jun 30;270(26):15827-31. 9: Umezawa H, Aoyagi T, Uotani K, Hamada M, Takeuchi T, Takahashi S. Ebelactone, an inhibitor of esterase, produced by actinomycetes J Antibiot (Tokyo). 1980 Dec;33(12):1594-6. <a href="https://pubmed.ncbi.nlm.nih.gov/2936359">10: Umezawa H. Low-molecular-weight immunomodifiers produced by micro-organisms Biotechnol Genet Eng Rev. 1985;3:255-73. </a> <br><strong>Products Related to Ebelactone A can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>