Pipazethate (hydrochloride)
Pipazethate (SKF 70230A; SQ 15874) hydrochloride is a potent GABA antagonist. Pipazethate hydrochloride shows antitussive activity and can be used in research in cough suppressant [1][2].
Product Specifications
CAS Number
6056-11-7
Product Name Alternative
SKF 70230A (hydrochloride) ; SQ 15874 (hydrochloride) ; Pipazetate (hydrochloride)
UNSPSC
12352005
Hazard Statement
H302-H315-H335
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pipazethate-hydrochloride.html
Smiles
O=C(N1C2=CC=CC=C2SC3=C1N=CC=C3)OCCOCCN4CCCCC4.Cl
Molecular Formula
C21H26ClN3O3S
Molecular Weight
435.97
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Squires RF, et al. Antidepressants and metabolites that block GABAA receptors coupled to 35S-t-butylbicyclophosphorothionate binding sites in rat brain. Brain Res. 1988 Feb 16;441 (1-2) :15-22. doi: 10.1016/0006-8993 (88) 91378-9.|[2]Vakil BJ, et al. Trial of pipazethate as an antitussive. Clin Pharmacol Ther. 1966 Jul-Aug;7 (4) :515-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
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