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5-HT2C agonist-4

5-HT2C agonist-4 (Compound 3i) is an agonist for 5-HT2C receptor with an EC50 of 5.7 nM. 5-HT2C agonist-4 reduces locomotor activity in the zebrafish larval model[1].

Product Specifications

CAS Number

2730085-33-1

UNSPSC

12352005

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/5-ht2c-agonist-4.html

Smiles

O=C(C1=C(/N=C/C2=CN(CC3=CC=CC=C3)C4=C2C=CC=C4)C(CCC)=NN1C)N

Molecular Formula

C24H25N5O

Molecular Weight

399.49

References & Citations

[1]Reddy GS, et al., Amberlyst-15 catalysed synthesis of novel indole derivatives under ultrasound irradiation: Their evaluation as serotonin 5-HT2C receptor agonists. Bioorg Chem. 2021 Nov;116:105380.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

5-HT2 Receptor; α-1 microglobulin

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