S-MGB-234 (TFA)
S-MGB-234 TFA is a minor groove binder used for African Animal Trypanosomiasis (AAT) . S-MGB-234 exhibits excellent in vitro activity against the primary pathogens of AAT: Trypanosoma congolense and Trypanosoma vivax. S-MGB-234 TFA does not show cross-resistance with current diamidine active molecules and is not internalized via the transporters used by diamidines[1].
Product Specifications
CAS Number
1970223-54-1
UNSPSC
12352005
Target
DNA/RNA Synthesis; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/s-mgb-234-tfa.html
Smiles
O=C(C1=CC=C(/C=C/C2=CC=C(OC)C=C2)N=C1)NC3=CN(C)C(C(NC4=CN(C)C(C(NCCC(N)=N)=O)=C4)=O)=C3.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F
Molecular Formula
C34H34F6N8O8
Molecular Weight
796.67
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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