AZ'9567
AZ9567 is a potent MAT2A inhibitor. AZ9567 exhibits antiproliferative activity against MTAP KO HCT116 cells with a pIC50 of 8.9[1].
Product Specifications
CAS Number
3056570-19-2
UNSPSC
12352005
Target
Methionine Adenosyltransferase (MAT)
Type
Reference compound
Related Pathways
Epigenetics; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/az-9567.html
Purity
99.21
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
O=C1C(C2=CC3=CN(C)N=C3C=C2)=CC(NN=C4C5CC5)=C4N1C6=CC=C(OC(F)F)C=C6
Molecular Formula
C24H19F2N5O2
Molecular Weight
447.44
References & Citations
[1]Atkinson SJ, et al. Development of a Series of Pyrrolopyridone MAT2A Inhibitors. J Med Chem. 2024 Mar 28;67 (6) :4541-4559.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
HA723677 100 µL
Mouse IFN gamma Recombinant Rabbit monoclonal Antibody
Sign In for Pricing
View Details 
PKSH030720 100 µg
Recombinant Human Mesothelin/MSLN Protein (aa 296-580, Fc Tag)
Sign In for Pricing
View Details 
TRC-C596145-5G 5 g
2-(2-Chloro-1-iminoethyl)-1,3,5-benzenetriol Hydrochloride
Sign In for Pricing
View Details