PROTAC TYK2 degrader-1
PROTAC TYK2 degrader-1 (CPD-155) is a PROTAC targeting degrader to TYK2 with Dmax >60%. (Structure Note: PINK, TYK2 ligand 1 ; Blue, VHL ligand Thalidomide (HY-14658) ; Black, linker)
Product Specifications
CAS Number
2770470-20-5
UNSPSC
12352005
Target
JAK; PROTACs
Type
Reference compound
Related Pathways
Epigenetics; JAK/STAT Signaling; PROTAC; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-tyk2-degrader-1.html
Purity
99.55
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CNC(C1=NN=C(C=C1NC2=CC=CC(C3=NN(C=N3)C)=C2OC)NC4=NC=C(C=C4)C(NCCCCCNC5=CC=CC6=C5C(N(C6=O)C7CCC(NC7=O)=O)=O)=O)=O
Molecular Formula
C40H41N13O7
Molecular Weight
815.84
References & Citations
[1]Jing Liu, et al. Tyrosine kinase 2 (tyk2) degradation compounds and methods of use. US20240059671A1. 2024-02-22.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Ferritin Conjugated Urtica dioica Lectin (Stinging Nettle) -UDA-
![2-[(Benzyloxycarbonyl)amino]-4,4,4-trifluorobutanoic Acid (>80%)](https://cdn.genprice.uk/products/572/1774825233278/imageurl/trc-b188946-500mg.webp)
2-[(Benzyloxycarbonyl)amino]-4,4,4-trifluorobutanoic Acid (>80%)
