Tubulin inhibitor 45
Tubulin inhibitor 45 (compound 5) is an inhibitor of tubulin protein active sites. Tubulin inhibitor 45 against MCF7 and HePG2 cancer cells with IC50 values of 11 μM and 13 μM[1].
Product Specifications
UNSPSC
12352005
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tubulin-inhibitor-45.html
Smiles
CC(N(C(C)=O)C1=C(C#N)C(CCC(C2=CC=CC=C2)C3)=C3S1)=O
Molecular Formula
C19H18N2O2S
Molecular Weight
338.42
References & Citations
[1]Amna S Elgubbi, et al. β-Enaminonitrile in the synthesis of tetrahydrobenzo[ b]thiophene candidates with DFT simulation, in vitro antiproliferative assessment, molecular docking, and modeling pharmacokinetics. RSC Adv. 2024 Jun 10;14 (26) :18417-18430.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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