SNC162
SNC162 is a delta-opioid receptor agonist with an IC50 of 0.94 nM. SNC162 has antidepressant-like and antinociceptiv effects[1][2].
Product Specifications
CAS Number
178803-51-5
UNSPSC
12352005
Target
Opioid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/snc162.html
Purity
99.72
Solubility
DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
C[C@@H](CN([C@@H](C1)C)CC=C)N1[C@@H](C2=CC=CC=C2)C3=CC=C(C=C3)C(N(CC)CC)=O
Molecular Formula
C27H37N3O
Molecular Weight
419.60
References & Citations
[1]Jutkiewicz EM, et al. Delta-opioid agonists: differential efficacy and potency of SNC80, its 3-OH (SNC86) and 3-desoxy (SNC162) derivatives in Sprague-Dawley rats. J Pharmacol Exp Ther. 2004 Apr;309 (1) :173-81.|[2]Banks ML, et al. Selective enhancement of fentanyl-induced antinociception by the delta agonist SNC162 but not by ketamine in rhesus monkeys: Further evidence supportive of delta agonists as candidate adjuncts to mu opioid analgesics. Pharmacol Biochem Behav. 2010 Dec;97 (2) :205-12.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
δ Opioid Receptor/DOR
Available Sizes
Frequently Asked Questions
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