SNC162

SNC162 is a delta-opioid receptor agonist with an IC50 of 0.94 nM. SNC162 has antidepressant-like and antinociceptiv effects[1][2].

Product Specifications

CAS Number

[178803-51-5]

UNSPSC

12352005

Target

Opioid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/snc162.html

Purity

99.72

Solubility

DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

C[C@@H](CN([C@@H](C1)C)CC=C)N1[C@@H](C2=CC=CC=C2)C3=CC=C(C=C3)C(N(CC)CC)=O

Molecular Formula

C27H37N3O

Molecular Weight

419.60

References & Citations

[1]Jutkiewicz EM, et al. Delta-opioid agonists: differential efficacy and potency of SNC80, its 3-OH (SNC86) and 3-desoxy (SNC162) derivatives in Sprague-Dawley rats. J Pharmacol Exp Ther. 2004 Apr;309 (1) :173-81.|[2]Banks ML, et al. Selective enhancement of fentanyl-induced antinociception by the delta agonist SNC162 but not by ketamine in rhesus monkeys: Further evidence supportive of delta agonists as candidate adjuncts to mu opioid analgesics. Pharmacol Biochem Behav. 2010 Dec;97 (2) :205-12.