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Imagabalin

Imagabalin (PD-0332334 free base) is an active compound with activity for studying neurological diseases. The synthesis of imagabalin involves the reaction of 3-methylvaleric acid and Meldrum acid. During the synthesis of imagabalin, an acyl chloride intermediate species, 3-methylvaleryl chloride, was revealed for the first time. The synthesis of imagabalin also provided new information about the reaction mechanism, indicating that 3-methylvaleric anhydride is an important intermediate[1].

Product Specifications

CAS Number

[610300-07-7]

Product Name Alternative

PD-0332334 (free base)

UNSPSC

12352211

Hazard Statement

H302-H315-H319-H335

Target

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/imagabalin.html

Smiles

OC(C[C@@H](N)C[C@H](C)CCC)=O

Molecular Formula

C9H19NO2

Molecular Weight

173.25

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]A detailed mechanistic investigation into the reaction of 3-methylpentanoic acid with Meldrum's acid utilizing online NMR spectroscopy

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 3

Curated Selection

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