Fostemsavir
Fostemsavir (BMS-663068) is the phosphonooxymethyl prodrug of BMS-626529. Fostemsavir (BMS-663068) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells.
Product Specifications
CAS Number
[864953-29-7]
Product Name Alternative
BMS-663068
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
HIV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/BMS-663068.html
Purity
99.69
Solubility
DMSO : 50 mg/mL (ultrasonic) |H2O : 20 mg/mL (ultrasonic)
Smiles
O=C(N1CCN(C(C2=CC=CC=C2)=O)CC1)C(C3=CN(COP(O)(O)=O)C4=C3C(OC)=CN=C4N5N=C(C)N=C5)=O
Molecular Formula
C25H26N7O8P
Molecular Weight
583.49
Precautions
H302, H312, H332
References & Citations
[1]Nowicka-Sans B, et al. In vitro antiviral characteristics of HIV-1 attachment inhibitor BMS-626529, the active component of the prodrug BMS-663068. Antimicrob Agents Chemother. 2012 Jul;56 (7) :3498-507.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
HIV-1
Available Sizes
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