Anti-virus agent 1

Anti-virus agent 1 (compound 4i), a phosphoramidate proagent of GS-5734 (HY-104077; Remdesivir), has potent antiviral activity. Anti-virus agent 1 is used for the research of coronavirus and Ebola virus (EBOV) [1][2].

Product Specifications

CAS Number

[1911578-83-0]

Product Name Alternative

Remdesivir isopropyl ester analog

UNSPSC

12352005

Target

Antibiotic

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/anti-virus-agent-1.html

Purity

99.01

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

O=[P@@](OC1=CC=CC=C1)(N[C@@H](C)C(OC(C)C)=O)OC[C@@H]2[C@@H](O)[C@@H](O)[C@@](C3=CC=C4N3N=CN=C4N)(C#N)O2

Molecular Formula

C24H29N6O8P

Molecular Weight

560.50

References & Citations

[1]Dustin Siegel , et al. Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-f][triazin-4-amino] Adenine C-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses. J Med Chem. 2017 Mar 9;60 (5) :1648-1661.|[2]Michael O' Neil Hanrahan Clarke, et al.Methods for treating arenaviridae and coronaviridae virus infections. US20170071964A1.