VUF 10214
Product Specifications
UNSPSC Description
VUF 10214 is a H4 receptor ligand with a pKi of 8.25. VUF 10214 exhibits significant anti-inflammatory activity in a carrageenan-induced paw edema rat model and can be used for research in the field of inflammatory diseases[1].
Target Antigen
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/vuf-10214.html
Smiles
O=C1NC2=C(N=C1N3CCN(CC3)C)C=C(C(Cl)=C2)Cl
Molecular Weight
313.18
References & Citations
[1]Smits RA, et al. Fragment based design of new H4 receptor-ligands with anti-inflammatory properties in vivo. J Med Chem. 2008 Apr 24;51(8):2457-67.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-119279/VUF-10214-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-119279/
Clinical Information
No Development Reported
CAS Number
848837-33-2
Curated Selection
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