(S) -BINAP

(S) -BINAP is the S-isomer of BINAP (HY-Y0003) . BINAP is a chiral bisphosphine ligand. (S) -BINAP can be used to assist in the synthesis of compounds with anticancer activity[1][2][3].

Product Specifications

CAS Number

[76189-56-5]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/s-binap.html

Purity

99.71

Solubility

DMSO : 2 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

C1(C=CC=C2)=C2[C@@]([C@@]3=C(C=CC=C4)C4=CC=C3P(C5=CC=CC=C5)C6=CC=CC=C6)=C(P(C7=CC=CC=C7)C8=CC=CC=C8)C=C1

Molecular Formula

C44H32P2

Molecular Weight

622.67

Precautions

H302, H315, H319, H335

References & Citations

[1]Tunik S P, et al. Reaction of (S) -BINAP with H4Ru4 (CO) 12. The First Example of Face-Bridging BINAP Coordination and 100% Stereoselectivity in Formation of a Chiral Tetranuclear Cluster Framework. Organometallics, 2004, 23 (3) : 568-579.|[2]Li M, et al. Stereoselective Total Synthesis of Formosanol, Tsugacetal, and Methyl β-Conidendral. Org Lett. 2022 Oct 28;24 (42) :7812-7816.|[3]Xin Jin, et al. Synthesis and characterization of a high-purity chiral 5,5'-disulfonato-BINAP ligand and its application in asymmetric hydrogenation of β-keto esters. Molecular Catalysis, 2021, 507, 111562.