Paeoniflorin

Paeoniflorin is a heat shock protein-inducing compound and commonly exists in the plants of Paeoniaceae family, with various biological activities, including anticancer activity, anti-inflammatory activity, enhancing cognition and attenuating learning impairment, anti-oxidative stress, antiplatelet aggregation, expansion of blood vessels, and reducing blood viscosity[1][2][3].

Product Specifications

CAS Number

[23180-57-6]

Product Name Alternative

Peoniflorin

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

HSP

Type

Natural Products

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

Applications

Neuroscience-Neurodegeneration

Field of Research

Cancer; Infection; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/paeoniflorin.html

Purity

98.94

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL

Smiles

O[C@H]1[C@H](O)[C@@H](O)[C@]([H])(O[C@]2([C@@]3(C)O[C@]4([H])O[C@@]5(C3)O)C[C@]5([H])[C@]24COC(C6=CC=CC=C6)=O)O[C@@H]1CO

Molecular Formula

C23H28O11

Molecular Weight

480.46

Precautions

H302, H315, H319, H335

References & Citations

[1]Yan-Xi Zhou, et al. A review on the pharmacokinetics of paeoniflorin and its anti-inflammatory and immunomodulatory effects. Biomed Pharmacother. 2020 Oct;130:110505.|[2]Yongjing Xiang, et al. Paeoniflorin: a monoterpene glycoside from plants of Paeoniaceae family with diverse anticancer activities. J Pharm Pharmacol. 2020 Apr;72 (4) :483-495.|[3]Dai Yan, et al. Paeoniflorin, a novel heat shock protein-inducing compound. Cell Stress Chaperones. 2004 Winter;9 (4) :378-89. Int J Oncol. 2013 Nov;43 (5) :1643-51.|[4]Pei-Pei Li, et al. BAFF/BAFF-R involved in antibodies production of rats with collagen-induced arthritis via PI3K-Akt-mTOR signaling and the regulation of paeoniflorin. J Ethnopharmacol. 2012 May 7;141 (1) :290-300.