Olanzapine N-oxide

Olanzapine N-oxide is a compound under investigation for the metabolism of antipsychotic compounds. Olanzapine N-oxidation and N-demethylation are catalyzed by different enzymes, and its plasma concentration and clearance are not affected by a single factor, such as a specific genotype or smoking behavior.

Product Specifications

CAS Number

[174794-02-6]

Product Name Alternative

(-)-Pindolol; (S)-(-)-Pindolol; S-Pindolol,ONO1111,ONO1101 (hydrochloride)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Others

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/olanzapine-n-oxide.html

Purity

98.02

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

CC(S1)=CC2=C1NC3=CC=CC=C3N=C2N4CC[N+](C)([O-])CC4

Molecular Formula

C17H20N4OS

Molecular Weight

328.43

Precautions

H302, H315, H319, H335

References & Citations

[1]Individual differences in in vitro and in vivo metabolic clearances of the antipsychotic drug olanzapine from non-smoking and smoking Japanese subjects genotyped for cytochrome P4502D6 and flavincontaining monooxygenase 3