Pheanthine
Pheanthine (Compound 2) is an antiplasmodial agent, that inhibits chloroquine-resistant Plasmodium falciparum K-1 (IC50 is 0.8 μM) and chloroquine-sensitive P. falciparum strain NF54 A19A (IC50 of 0.03 μM) . Pheanthine exhibits low cytotoxicity in human lung fibrosblast (MRC-5, IC50 is 11.2 μM) and macrophages (PMM, IC50 is 8 μM) [1].
Product Specifications
CAS Number
1263-79-2
UNSPSC
12352005
Target
Parasite
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/pheanthine.html
Solubility
10 mM in DMSO
Smiles
COC1=C(OC(C=C2C(CC3)=C4)=C4OC)C([C@@](N5C)([H])CC(C=C6OC(C=C7)=CC=C7C[C@@]2([H])N3C)=CC=C6OC)=C(CC5)C=C1OC
Molecular Formula
C38H42N2O6
Molecular Weight
622.75
References & Citations
[1]Cimanga Kanyanga R., et al., Isolation and structure elucidation of two antiprotozoal bisbenzylisoquinoline alkaloids from Triclisia gilletii stem bark. Phytochemistry Letters. 2018.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
ARP57063_P050-HRP 100 µL
Ppp2r3c Antibody - N-terminal region : HRP (ARP57063_P050-HRP)
Sign In for Pricing
View Details AZC9V3N7-Fluoro647 100 µg/Vial
Anti-Zebrafish PR/PGR Antibody Picoband® Fluoro647 Conjugated
Sign In for Pricing
View Details 
sc-436616-LAC 200 µL
β-defensin 48 Lentiviral Activation Particles (m)
Sign In for Pricing
View Details