Sudan IV-d6
Sudan IV-d6 (Solvent Red 24-d6) is the deuterium labeled Sudan IV. Sudan IV is an agonist of the aryl hydrocarbon receptor (AhR) that activates downstream signaling pathways and induces CYP1A1 expression. Sudan IV promotes CYP1A1 gene transcription by activating AhR-ARNT heterodimers and binding to exogenous response elements (XREs) on DNA, thereby enhancing drug metabolizing enzyme activity. Sudan IV can be used to study the toxicity mechanisms of industrial dyes and the effects of interactions with serum proteins (such as bovine serum albumin (BSA) ) on their distribution in vivo. Sudan IV is a fat-soluble diazo dye that can be used to stain lipids, triglycerides, and lipoproteins on frozen sections[1][2][3][4].
Product Specifications
CAS Number
1014689-18-9
Product Name Alternative
Solvent Red 24-d6; C.I. 26105-d6
UNSPSC
12352005
Target
Aryl Hydrocarbon Receptor; Biochemical Assay Reagents; Cytochrome P450; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; Others
Field of Research
Metabolic Disease
Smiles
OC1=C([2H])C([2H])=C2C([2H])=C([2H])C([2H])=C([2H])C2=C1/N=N/C3=CC=C(C=C3C)/N=N/C4=CC=CC=C4C
Molecular Formula
C24H14D6N4O
Molecular Weight
386.48
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
CYP1
Frequently Asked Questions
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