DOTA-NOC

DOTA-NOC (DOTA-Nal3-octreotide) is a high-affinity ligand of somatostatin receptor subtypes 2, 3 and 5. DOTA-NOC can be used for labeling with various radiometals, and development of radiopeptide imaging[1]. DOTA-NOC can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs) .

Product Specifications

CAS Number

[619300-53-7]

Product Name Alternative

DOTA-Nal3-octreotide

UNSPSC

12352209

Target

Radionuclide-Drug Conjugates (RDCs) ; Somatostatin Receptor

Type

Peptides

Related Pathways

Antibody-drug Conjugate/ADC Related; GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/dota-noc.html

Purity

99.22

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C([C@@H](NC([C@H](CSSC[C@H](NC([C@](NC([C@@H](NC1=O)CCCCN)=O)([H])[C@H](O)C)=O)C(N[C@H](CO)[C@H](O)C)=O)NC([C@H](NC(CN2CCN(CCN(CCN(CC2)CC(O)=O)CC(O)=O)CC(O)=O)=O)CC3=CC=CC=C3)=O)=O)CC4=CC=CC5=C4C=CC=C5)N[C@@H]1CC6=CNC7=CC=CC=C67

Molecular Formula

C69H94N14O17S2

Molecular Weight

1455.70

References & Citations

[1]Wild D, et al. DOTA-NOC, a high-affinity ligand of somatostatin receptor subtypes 2, 3 and 5 for labelling with various radiometals. Eur J Nucl Med Mol Imaging. 2003 Oct;30 (10) :1338-47.