Dabigatran etexilate (mesylate)
Product Specifications
UNSPSC Description
Dabigatran etexilate mesylate (BIBR 1048MS) is an orally active proagent of Dabigatran (a direct inhibitor of thrombin). Dabigatran etexilate mesylate has anticoagulant effects and is used for the prophylaxis of venousthromboembolism and stroke due to atrial fibrillation[1].
Target Antigen
Thrombin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Dabigatran-etexilate-mesylate.html
Purity
99.93
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C(N(C1=NC=CC=C1)CCC(OCC)=O)C2=CC=C3C(N=C(N3C)CNC4=CC=C(C(NC(OCCCCCC)=O)=N)C=C4)=C2.CS(=O)(O)=O
Molecular Weight
723.84
References & Citations
[1]Wienen W, et al. In-vitro profile and ex-vivo anticoagulant activity of the direct thrombin inhibitor dabigatran and its orally activeprodrug, dabigatran etexilate. Thromb Haemost. 2007 Jul;98(1):155-62.|[2]Blair HA, Keating GM. Dabigatran Etexilate: A Review in Nonvalvular Atrial Fibrillation. Drugs. 2017;77(3):331-344. J Chromatogr Sci. 2016 Jul 29;54(9):1648-1651.|Biochem Pharmacol. 2016 Nov 1;119:76-84.|Elife. 2022 Mar 23:11:e77444.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-10274A/Dabigatran-etexilate-mesylate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-10274A/Dabigatran-etexilate-mesylate-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
872728-81-9
Available Sizes
Curated Selection
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