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Dabigatran etexilate (mesylate)

Product Specifications

UNSPSC Description

Dabigatran etexilate mesylate (BIBR 1048MS) is an orally active proagent of Dabigatran (a direct inhibitor of thrombin). Dabigatran etexilate mesylate has anticoagulant effects and is used for the prophylaxis of venousthromboembolism and stroke due to atrial fibrillation[1].

Target Antigen

Thrombin

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Dabigatran-etexilate-mesylate.html

Purity

99.93

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=C(N(C1=NC=CC=C1)CCC(OCC)=O)C2=CC=C3C(N=C(N3C)CNC4=CC=C(C(NC(OCCCCCC)=O)=N)C=C4)=C2.CS(=O)(O)=O

Molecular Weight

723.84

References & Citations

[1]Wienen W, et al. In-vitro profile and ex-vivo anticoagulant activity of the direct thrombin inhibitor dabigatran and its orally activeprodrug, dabigatran etexilate. Thromb Haemost. 2007 Jul;98(1):155-62.|[2]Blair HA, Keating GM. Dabigatran Etexilate: A Review in Nonvalvular Atrial Fibrillation. Drugs. 2017;77(3):331-344. J Chromatogr Sci. 2016 Jul 29;54(9):1648-1651.|Biochem Pharmacol. 2016 Nov 1;119:76-84.|Elife. 2022 Mar 23:11:e77444.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-10274A/Dabigatran-etexilate-mesylate-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-10274A/Dabigatran-etexilate-mesylate-SDS-MedChemExpress.pdf

Clinical Information

Launched

CAS Number

872728-81-9

Available Sizes

Curated Selection

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