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Human IL-1α/IL1A Protein

Human IL-1α/IL1A protein, expressed in E.coli

Product Specifications

Background

IL-1α a member of the interleukin 1 cytokine family. Interleukin 1 (IL-1) is a name that designates two proteins, IL-1α and IL-1β, which are the products of distinct genes, but which show approximately 25% amino acid sequence identity and which recognize the same cell surface receptors. IL-1α stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity.

Product Name Alternative

BAF; Hematopoietin-1; IL1 alpha; IL-1 alpha; IL1; IL1A; IL-1A; IL1-ALPHA; IL1F1; IL-1F1; IL1F1hematopoietin-1; interleukin 1, alpha; interleukin-1 alpha; LAF; LEM; preinterleukin 1 alpha; pro-interleukin-1-alpha

Gene ID

3552

Accession Number

P01583

Tag

IL-1α/IL1A

Type

Cytokines and proteins

Applications

No tag

Purity

> 95 % as determined by SDS-PAGE

Activity

Testing in progress

Molecular Weight

18 kDa

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Features & Benefits

Endotoxin: < 1 EU per µg of the protein as determined by the LAL method.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Lyophilized Human IL-1α/IL1A proteinshould be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles.

Protein Length

The recombinant Human IL-1α protein consists of 160 amino acids (N-Met) and has a predicted molecular mass of 18 kDa. The apparent molecular mass of the Human IL-1α protein is approximately 18 kDa in SDS-PAGE under reducing conditions due to glycosylation.

Formulation

Lyophilized from sterile 20 mM Tris, 150 mM NaCl, pH7.5.

Applications Notes

Human

Other Product Names

BAF; Hematopoietin-1; IL1 alpha; IL-1 alpha; IL1; IL1A; IL-1A; IL1-ALPHA; IL1F1; IL-1F1; IL1F1hematopoietin-1; interleukin 1, alpha; interleukin-1 alpha; LAF; LEM; preinterleukin 1 alpha; pro-interleukin-1-alpha

Recommended Usage

Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Human IL-1α protein using the buffer we provided not less than 100 µg/mL, which can then be further diluted to other aqueous solutions.

Preparation

E.coli

Accession Number URL

https://www.uniprot.org/uniprot/P01583

AA Sequence

Amino acid sequence derived from Human IL-1α protein isoform (P01583-1, Ser113-Ala271) was expressed.

Available Sizes

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