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Human IL-2 Protein

Human IL-2 protein, expressed in E. coli

Product Specifications

Background

Interleukin (IL-2) abbreviated as interleukin, refers to a lymphokine that interacts between leukocytes or immune cells, and it belongs to the same cytokine as blood cell growth factor. The two coordinate and interact with each other to complete hematopoietic and immune regulation functions together. Interleukins play an important role in transmitting information, activating and regulating immune cells, mediating the activation, proliferation and differentiation of T and B cells, and in inflammation.

Product Name Alternative

Interleukin-2; IL-2; T-Cell Growth Factor; TCGF; Aldesleukin; IL2

Gene ID

3558

Accession Number

P60568

Tag

IL-2

Type

Cytokines and proteins

Applications

No tag

Purity

> 98 % as determined by SDS-PAGE

Activity

Measured by its ability to induce proliferation in CTLL-2 cells.The ED50 for this effect is 2.269 ng/ml.

Molecular Weight

15.5 kDa

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Features & Benefits

Endotoxin: < 1.0 EU per µg of the protein as determined by the LAL method.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Lyophilized Human IL-2 protein protein product should be stored desiccated below-18°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below-18°C. For long term storage it is recommended to add a carrier protein (0.1% HSAor BSA) . Please prevent freeze-thaw cycles

Protein Length

The recombinant human IL-2 consists of 134 amino acids (N-Met) and has a predicted molecular mass of 15.5 KD. The apparent molecular mass of the human IL-2 is approximately 16 KD in SDS-PAGE under reducing conditions due to glycosylation.

Formulation

Lyophilized from sterile 20 mM Tris, 50 mM NaCl, pH 5.0, 1 mM DTT,1 mM EDTA

Applications Notes

Human

Other Product Names

Interleukin-2; IL-2; T-Cell Growth Factor; TCGF; Aldesleukin; IL2

Recommended Usage

Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Human IL-2 protein protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions

Preparation

E. coli

Accession Number URL

https://www.uniprot.org/uniprot/P60568

AA Sequence

Amino acid sequence derived from human IL-2 isoform (P60568-1) (Ala21-Thr153) was expressed.

Available Sizes

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