CYY292
Product Specifications
UNSPSC Description
CYY292 is an FGFR1 inhibitor that specifically targets the FGFR1/AKT/Snail pathway in GBM cells. CYY292 dose-dependently inhibits cancer cell proliferation, epithelial-mesenchymal transition, stemness, invasion, and migration in vitro[1].
Target Antigen
FGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
cancer
Assay Protocol
https://www.medchemexpress.com/cyy292.html
Solubility
10 mM in DMSO
Smiles
CN1CCN(C2=C(OC)C=C(NC3=NC(NC4=CC(NN=C5)=C5C=C4)=C(C)C=N3)C=C2)CC1
Molecular Weight
444.53
References & Citations
[1]Bi Y, et al. A novel FGFR1 inhibitor CYY292 suppresses tumor progression, invasion, and metastasis of glioblastoma by inhibiting the Akt/GSK3β/snail signaling axis. Genes Dis. 2023 Apr 3;11(1):479-494.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162153/CYY292-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162153/
Clinical Information
No Development Reported
CAS Number
2644673-04-9
Available Sizes
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