Coclauril

Coclauril is an inhibitor of HBV. Coclauril inhibits HBV replication in the human hepatoblastoma cell line with an EC50 of 7.6 μg/mL[1].

Product Specifications

CAS Number

[127350-68-9]

UNSPSC

12352211

Hazard Statement

H302-H315-H319-H335

Target

HBV

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/coclauril.html

Solubility

10 mM in DMSO

Smiles

N#C/C=C1C=C[C@H](O)C[C@@H]\1O

Molecular Formula

C8H9NO2

Molecular Weight

151.16

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Yi XX, et al. Four New Cyclohexylideneacetonitrile Derivatives from the Hypocotyl of Mangrove (Bruguiera gymnorrhiza) . Molecules. 2015 Aug 12;20 (8) :14565-75.|[2]YOGO Motoi, et al. Coclauril, a nonglucosidic 2-cyclohexen-1-ylideneacetonitrile, from Cocculus lauriforius DC.. CHEMICAL & PHARMACEUTICAL BULLETIN, 38 (1), 225–226.