CYP51-IN-21
CYP51-IN-21 (Compound A33) is a potent CYP51 inhibitor. CYP51-IN-21 shows excellent antifungal activities against pathogenic fungi and drug-resistant strains. CYP51-IN-21 inhibits the formation of fungal biofilm[1].
Product Specifications
CAS Number
3053864-59-5
UNSPSC
12352005
Target
Cytochrome P450
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cyp51-in-21.html
Smiles
OC(CN(C)CC1=CC=C(N2CCN(CC3=C(Br)C=C(F)C=C3)CC2)C=C1)(CN4N=CN=C4)C5=CC=C(F)C=C5F
Molecular Formula
C30H32BrF3N6O
Molecular Weight
629.51
References & Citations
[1]Sun Y, et al. Identification of novel and potent triazoles targeting CYP51 for antifungal: Design, synthesis, and biological study. Eur J Med Chem. 2024 Oct 5;280:116942.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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