ST-1892
ST-1892 (compound 14) is a highly potent FXR agonist (EC50=7.2 nM) that can be used to study diseases or disorders caused by metabolic inflammation[1].
Product Specifications
CAS Number
[1409411-32-0]
UNSPSC
12352005
Target
FXR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/st-1892.html
Smiles
O=C(C1=CC=CC(C2=NC(C3=CC=CC=C3C)=NO2)=C1)O
Molecular Formula
C16H12N2O3
Molecular Weight
280.28
References & Citations
[1]Flesch D, et al. Fragmentation of GW4064 led to a highly potent partial farnesoid X receptor agonist with improved drug-like properties[J]. Bioorganic & medicinal chemistry, 2015, 23 (13) : 3490-3498.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-117918/ST-1892-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-117918/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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