Artemisone

Artemisone (Artemifone) is a potent and semi-synthetic antimalarial, inhibits P. falciparum strains, with a mean IC50 of 0.83 nM[1]. Artemisone is also a potent inhibitor of human CMV[2].

Product Specifications

CAS Number

[255730-18-8]

Product Name Alternative

Artemifone; BAY 44-9585

UNSPSC

12352005

Target

CMV; Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Artemisone.html

Purity

98.0

Solubility

DMSO : 130 mg/mL (ultrasonic)

Smiles

C[C@H]1[C@H](N2CCS(CC2)(=O)=O)O[C@@]3([H])[C@]45[C@@]([C@H](C)CC[C@]51[H])([H])CC[C@@](O3)(C)OO4

Molecular Formula

C19H31NO6S

Molecular Weight

401.52

References & Citations

[1]Vivas L, et al. Antimalarial efficacy and drug interactions of the novel semi-synthetic endoperoxide artemisone in vitro and in vivo. J Antimicrob Chemother. 2007 Apr;59 (4) :658-65.|[2]Ruiyuan Cao, et al. Anti-SARS-CoV-2 Potential of Artemisinins In Vitro. ACS Infect. Dis. 2020 Jul.