Celivarone

Celivarone (SSR149744C) is a orally active noniodinated benzofuran derivative with antiarrhythmic properties. Celivarone has the potential for atrial fibrillation and in ventricular arrhythmias research[1].

Product Specifications

CAS Number

401925-43-7

Product Name Alternative

SSR149744C

UNSPSC

12352005

Hazard Statement

H317-H373

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/celivarone.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC2=C(OC(CCCC)=C2C(C3=CC=C(CCCN(CCCC)CCCC)C=C3)=O)C=C1)OC(C)C

Molecular Formula

C34H47NO4

Molecular Weight

533.74

Precautions

P260-P261-P272-P280-P302+P352-P362+P364-P501

References & Citations

[1]Avinash R Khitri, et al. Celivarone for maintenance of sinus rhythm and conversion of atrial fibrillation/flutter. J Cardiovasc Electrophysiol. 2012 May;23 (5) :462-72.|[2]Patrick Gautier, et al. In vivo and in vitro antiarrhythmic effects of SSR149744C in animal models of atrial fibrillation and ventricular arrhythmias. J Cardiovasc Pharmacol. 2005 Feb;45 (2) :125-35.