Celivarone
Celivarone (SSR149744C) is a orally active noniodinated benzofuran derivative with antiarrhythmic properties. Celivarone has the potential for atrial fibrillation and in ventricular arrhythmias research[1].
Product Specifications
CAS Number
401925-43-7
Product Name Alternative
SSR149744C
UNSPSC
12352005
Hazard Statement
H317-H373
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/celivarone.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC2=C(OC(CCCC)=C2C(C3=CC=C(CCCN(CCCC)CCCC)C=C3)=O)C=C1)OC(C)C
Molecular Formula
C34H47NO4
Molecular Weight
533.74
Precautions
P260-P261-P272-P280-P302+P352-P362+P364-P501
References & Citations
[1]Avinash R Khitri, et al. Celivarone for maintenance of sinus rhythm and conversion of atrial fibrillation/flutter. J Cardiovasc Electrophysiol. 2012 May;23 (5) :462-72.|[2]Patrick Gautier, et al. In vivo and in vitro antiarrhythmic effects of SSR149744C in animal models of atrial fibrillation and ventricular arrhythmias. J Cardiovasc Pharmacol. 2005 Feb;45 (2) :125-35.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
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