N-Hydroxypipecolic acid

N-Hydroxypipecolic acid (1-Hydroxy-2-piperidinecarboxylic acid), a plant metabolite and a systemic acquired resistance (SAR) regulator, orchestrates SAR establishment in concert with the immune signal salicylic acid. N-Hydroxypipecolic acid accumulates systemically in the plant foliage in response to pathogen attack. N-Hydroxypipecolic acid induces SAR to bacterial and oomycete infection[1][2][3].

Product Specifications

CAS Number

[115819-92-6]

Product Name Alternative

1-Hydroxy-2-piperidinecarboxylic acid; NHP

UNSPSC

12352005

Hazard Statement

H302, H312, H332

Target

Bacterial

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/n-hydroxypipecolic-acid.html

Purity

98.0

Solubility

DMSO : 25 mg/mL (ultrasonic; warming; heat to 80°C) |H2O : 50 mg/mL (ultrasonic)

Smiles

O=C(C1N(O)CCCC1)O

Molecular Formula

C6H11NO3

Molecular Weight

145.16

Precautions

H302, H312, H332

References & Citations

[1]Shan L, et al. Pipped at the Post: Pipecolic Acid Derivative Identified as SAR Regulator. Cell. 2018 Apr 5;173 (2) :286-287.|[2]Ádám AL, et al. Signals of Systemic Immunity in Plants: Progress and Open Questions. Int J Mol Sci. 2018 Apr 10;19 (4) . pii: E1146.|[3]Hartmann M, et al. N-hydroxypipecolic acid and salicylic acid: a metabolic duo for systemic acquired resistance. Curr Opin Plant Biol. 2019 Aug;50:44-57.